Syringe Replacement Procedure for Efficient Fluid Handling in Pump Systems
The ASP-SY0360 is a compact OEM industrial syringe pump module designed for precision liquid handling applications. This syringe pump can communicate through RS-232, RS-485, or CAN interfaces, allowing for multi-pump arrangements of up to 15 pumps in one group. It supports group control and individual addressing, making it versatile for various automation needs.
This pump is ideal for tasks such as auto pipetting, sample dilution or mixing, and sample dispensing in analytical instruments. Industrial syringe pumps find wide application in analytical instruments, including precision liquid handling or delivery, pharmaceutical industry, microfluidics systems, integration with analytical instruments for sample preparation, auto sampling for in vitro diagnostics (IVD), flow injection systems, ammonia nitrogen analyzers, and other precision metering applications such as mass spectrometers and flow cytometers.
The wetted materials in the flow path are borosilicate glass, PTFE, and PCTFE/Sapphire, and can be customized upon request. The pump can accept different sizes of glass syringes from 25µL to 25mL, enabling syringe replacement. For the syringe replacement procedure and more details, please refer to the follow steps or contact our product specialist for assistance.

Figure 1 ASP-SY0360 Industrial Syringe Pump Configuration
Step 1: Empty the syringe and flow path, and disconnect all fittings and tubing.
Step 2: Unscrew the Thumb Screw using the M4 Allen wrench provided in the original package.
Step 3: Send the following ASCII commands to the pump to initialize the pump and valve: /1ZR, /1I1A6000R (Move the Plunger Seat to the maximum stroke to the bottom of the pump)
Step 4: Unscrew the original glass syringe clockwise in the vertical direction, ensuring no damage to the syringe threads on the switching valve port.
Step 5: Pull the plunger in the new glass syringe to its maximum stroke and align the plunger end with the Plunger Seat by aligning the hole. Ensure the plunger is vertically aligned when threaded counterclockwise into the female ¼”-28 hole on the switching valve.
Step 6: Reinitialize and move the Plunger Seat to the home position.
Step 7: Manually move the syringe plunger to the bottom of the syringe and align the hole with the Plunger Seat. Use the Thumb screw to tighten the Plunger Seat and the Plunger of the glass syringe.
Step 8: After installation, reconnect the tubing to the female threaded ports on the switching valve.
Step 9: Run the following ASCII codes: /1ZR, /1I1A6000R, /1A0R (to aspirate 6000 full steps to Port 1 and dispense all liquid back to the beaker). Check for any leakage during aspirate and dispense.
Step 10: If leakage is observed, inspect the flow path and tighten the fittings to avoid further leakage.
Figure 2. Unscrew the Thumb Screw on the Plunger

Figure 3. Align the Syringe Pump with the Plunger Seat
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Aurora Pro Scientific provides innovative syringe and piston pumps designed for precision fluid handling in laboratory and industrial settings. Our offerings include programmable syringe pumps with touchscreen controls and customizable infusion/withdrawal modes, compact OEM syringe pumps for specialized integration, high-volume piston pumps with solenoid valves for automation, and fixed-volume syringe pumps with integrated glass syringes for accurate dosing. They also feature multi-channel syringe pumps for synchronized, parallel fluid handling, enhancing efficiency and adaptability in diagnostics, research, and automation.
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Tags Sample Preparation, HPLC, Syringe Pump, Analytical Instrument









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