Cellulose Acetate (CA) membranes are a mixture of cellulose triacetate and diacetate creating a strong membrane in both lateral and longitudinal directions.  Compared to MCE membrane, CA exhibits improved solvent resistance to low molecular weight alcohols, improved heat resistance up to 180˚C, and may be repeatedly autoclaved or steam-sterilized without loss of integrity.

These membranes have a very low static charge which can minimize particle contamination of the membrane.  This characteristic makes CA membrane ideally suited for OEM applications.  Recovery of fastidious gram+ organisms may be enhanced by culturing on CA membrane. 

CA membranes are low protein binding and have low aqueous extractables(0.1%wt). Typical applications include filtration of enzyme solutions to minimize protein loss, diagnostic cytology, receptor binding studies, and filtration of solutions containing alcohol.

Key Features

• Composition: Mixture of cellulose triacetate and diacetate
• Characteristics: Low static charge and high strength
• Autoclavable: Withstands autoclaving temperatures up to 130℃without adversely affecting bubble point, flow rate or microbiological recovery
• Clean: Lowest aqueous extractables (0.1 wt%)of all Advantec membranes
• Relative to MCE (Mixed Cellulose Esters, Nitrocellulose):

• Improved solvent resistance to low molecular 
• Better heat resistance
• Lower protein binding
• Pore size: 0.2, 0.45, 0.8 and 3µm
• Diameter: 13 mm, 25 mm,  37mm, 47mm, 90 mm, 142 mm, and 293 mm.
• Packaged as nonsterile bulk packs or sterile individually wrapped
  

Typical Applications

• Filtration of enzyme solutions to minimize protein loss
• Enhanced recovery of fastidious gram positive organisms 
• Diagnostic cytology
  
• Receptor binding studies
• Filtration of solutions containing alcohol 

Note: Should not be prewet prior to loading into a holder and autoclaving