• PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips
    PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips PDMS-Glass-Polycarbonate  Hybrid Microfluidic Chips

A series of off-the-shelf microfluidic chips are offered with functions of droplet generation, mixing, gradient generation, electrophoresis, shear force measurement, hydrodynamic flow focusing, and filtration. The top plate of the microfluidic chips consists of a plastic (polycarbonate, or PMMA) layer with molded luer connector and one thin elastomer layer as a bonding adhesive. The structure of bottom layer has three options: A- Plastic layer, B- Elastomer, C-Glass layer. The microfluidic channel network can be patterned either on the top plate or on the bottom plate.

Key Features

  • Cost effective 
  • Standard Luer connectors to support plugs and perform operations
  • Multiple structure options
  • Reversible assembly (for some chips)  
  • Standard overall size:  25 mm x 55 mm x 3 mm 

Typical Applications

  • Compound synthesis
  • Study of reaction kinetics 
  • Single cell analysis 
  • Liquid biopsy 
  • Shear stress on cell physical properties 
  • Circulating tumor cells (CTC) 
  • Cell counting and sorting 
  • Drug discovery 
  • Cell culture 
  • Tissue engineering


Minimum order of  20 chips.  Contact us if you want to order an amount of chips that is not an increment of 5 units.  We contact customers prior to custom microfluidic chip fabrication to confirm parameters and specific requirements.  If you do not see the specifications you require, need clarification or a quote, please contact us via email


Product Part Number
Dimensions
Application Notes

P1E-13-001: Droplet Generation Microfluidic Chip


50 µm of minimum width/depth for droplet generation, thus generating adjustable droplets at 50-200 µm in diameter.                                                                                                                                        

Droplet microfluidic chips are usually used as micro-reactors to study microscale reactions and processes. The advantages include small volumes, rapid mixing, no sample dispersion, no cross contamination, and well-maintained conditions. These microfluidic chips can find  applications in compound synthesis and studies of reaction kinetics.

P1E-13-002: Droplet Generation Microfluidic Chip


50 µm of minimum width/depth for droplet generation, thus generating adjustable droplets at 50-200 µm in diameter.

Droplet microfluidic chips are usually used as micro-reactors to study microscale reactions and processes. The advantages include small volumes, rapid mixing, no sample dispersion, no cross contamination, and well-maintained conditions These  microchips can find applications in compound synthesis, study of reaction kinetics, single-cell analysis, and optimization of protein crystallization, etc. 

P1E-13-003: Microfluidic Shear Chip


200 µm minimum and 1 mm maximum in channel width. The main channel dpth is about 50 µm.

The shear stress directly affects cell physical and biological properties thus playing a critical role in cell viability. The shear  microfluidic chip can be used with other instruments to measure the shear force effect on cell properties, such as phenotype.

P1E-13-004: Spiral Microfluidic Chip


Channel at 300 µm in width and 50 µm in depth.

Particles with different sizes can achieve their own equilibria due to the inertial lift and viscous drag forces at distinct streamlines of the spiral micro channel. . This microchip can be applied to the isolation of circulating tumor cells from peripheral blood.

P1E-14-005: Y- Microfluidic Chip

Channel at 200 µm in width and 50 µm.

To generate layered flows with different compositions or to perform mixing of two flows, etc.

P1E-14-006: Microfluidic Gradient Generator

Main channel at 100 µm in width/depth

The microfluidic gradient generator can generate linear or nonlinear chemical concentration gradients by restricting the inter-diffusion between two adjacent streams of different concentrations with the specially designed channel networks. This microchip can find a variety of in vitro applications, such as cellular responses to chemical gradients, cell migration and proliferation, etc.

P1E-14-007: Mixing Microfluidic Chip


200 µm minimum and 1 mm maximum in channel width. The main channel is 50 µm in depth.

Performing mixing of two fluids based on laminar flow diffusion

P1E-16-008: Electrophoresis Microfluidic Chip


Channel at 100 µm in width/depth

Separating different ions or molecules based on capillary electrophoresis

P1E-16-009A: 2D Flow Focusing Microfluidic Chip


Channel at 100 µm in width and 50 µm in depth

The 3-inlet microfluidic chip can generate hydrodynamic flow focusing of the core sample flow, and the core flow may contain analytes or cells of interest. The flow focusing can be used in numerous applications, such as droplet generation, rapid biochemical kinetics, single cell counting and analysis, and drug discovery.

P1E-16-009B: 3D Flow Focusing Microfluidic chip


Channel at 100 µm in width and 50 µm in depth

The microfluidic chip features simple one-step 3D hydrodynamic focusing of a sample fluid stream injected from the center inlet. The width and depth of the sample stream can be confined down to a few micrometers regime. This chip can be used in microfluidic cytometry for single cell analysis, cell sorting, and test of circulating tumor cells (CTC).

P1E-1X-010: Drug Screening Microfluidic Chip


Channel at 100 µm in width and 50 µm in depth

Performing parallel drug screening by using multiple microfluidic channels.

P1E-16-011: Cell Migration Microfluidic Chip


100 µm in width  and 50 µm in depth

Study of cell migration in a specific chemical gradient

P1E-32-100: Microfluidic Filtration Chip


Pore size: 5-8 µm
Membrane diameter: 13 mm
Membrane thickness: 40 µm
Main channel dimension: 0.5 mm x 0.5 mm

This microfluidic filtration chip integrates a filtration membrane with pores to isolate and capture cells or particles by size. The chip can be used in capturing rare cells present in blood of cancer patients for immunocytochemistry (ICC) analysis.

P1E-34-200: Organ Microfluidic Chip


Main channel dimension: 0.5 mm x 0.5 mm

Mimicking internal environment of human beings to establish organ models for in vitro culture of tissues or stem cells that can differentiate to skin, heart, lung, liver, neuron, and kidney, etc.  When a tissue patch is placed between the two plates, culture media containing different factors can flow in the upper and lower chambers separated by the patch.

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PDMS-Glass-Polycarbonate Hybrid Microfluidic Chips

  • Product Code: Chip-002
  • Availability: In Stock
  • $31.25


Available Options


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Tags: Microfluidic, Circulating tumor cells, Cell Counting